For example, the hydroxyl group can undergo glucuronic acid conjugation, sulfate conjugation and acetylation reactions
Its what drives the fatigue you cant explain, the dull recovery after workouts, and the faster-than-expected aging you notice in the mirror
doi:10.1016/j.redox.2013.08.006 Lin SX, Lisi L, Russo CD, Polak PE, Sharp A, Weinberg G, Kalinin S, Feinstein DL (2011) The anti-inflammatory effects of dimethyl fumarate in astrocytes involve glutathione and haem oxygenase-1
Observational studies in humans, while limited in number, provide intriguing evidence supporting a role for melatonin in the context of AD