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It is a vitamin that is soluble in water, so any excess amount that the body does not need gets flushed out of our systems

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Furthermore, the requirement for patients to have an available weight measurement on the index date and after 1 year of follow-up and to be persistent on therapy for 1 year may have introduced potential selection bias in favor of patients who are more actively managed and/or for whom treatment is effective

The in vivo study showed a significant reduction in TMAO levels in C57BL/6(FMO3 +/+ ) strain WT mouse models and in TMA levels in C57BL/6 -Fmo3em1Smoc (KO) mouse models