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Sterile water lacks the bacteriostatic agent, meaning bacteria can begin to grow after the first use, contaminating the entire vial
The largest retrospective study that reviewed 472 reported cases showed mainly maxillary involvement in 279 cases (62.2%), followed by the skull (70
The most common adverse effects are mild gastrointestinal symptoms (nausea, vomiting, diarrhea) that typically occur at rates similar to placebo in controlled trials
This anatomical reality explains why a muscle strain might heal in days while a tendon injury can linger for months
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