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Journal of Neuroscience Research 92 (4): 446-54
Acute ischemia by a variety of mechanisms, including stimulation of N -methyl-d-aspartate (NMDA) receptors, mitochondrial dysfunction, activation of neuronal nitrite oxidase (NOS), induction of NOS by cyclooxygenase 2, autooxidation of catecholamines, and metabolism of free fatty acid such as arachidonic acid can increase the production of free radicals [38, 39]
Kelley EE, Khoo NK, Hundley NJ, Malik UZ, Freeman BA, Tarpey MM
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