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Intriguingly, this study regarding elevated glutamine metabolism in cancer cells also showed that glutaminolysis could in turn reinforce metabolic reprogramming, thus implying that glutamine metabolism plays a crucial role in tumorigenesis and tumor progression 16 (Fig
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Through binding with KAP-1 or coordinating with the DNA methylation machinery, SETDB1 can target multiple genomic loci in different cell types or at different stages during brain development (Padeken et al., 2022).In the early stages of brain development, Setdb1 is highly expressed in proliferating neural progenitor cells
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