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Infrequent passing of stool also increases bacterial fermentation of luminal content in the small and large intestines, producing gases including hydrogen, methane, and carbon dioxide, which may contribute to distension, flatulence, and abdominal pain [23]

Gong et al., 2024), result in DNA lesion formation and thiol group oxidation

This provides evidence for the role of EGT in establishing virulent infection of Mtb in the mouse lungs and for pathological progression of disease