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In a 2015 review in BioMed Research International , Pickart, Vasquez-Soltero and Margolina collated Connectivity Map data showing GHK modulates expression of roughly 31 percent of profiled human genes in cultured fibroblasts
TB-500, by contrast, acts systemically by mobilizing endothelial precursors, regulatory T-cells, and stem cells throughout the body
It also significantly reduced inflammatory markers TNF-alpha and destructive enzymes MMP-2/MMP-9
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