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Because of the 1:1 exchange of cystine and glutamate across the cell membrane, a large amount of glutamate is exported with an upregulation of SLC7A11 (53)
An experiment using human peripheral blood macrophages (M) showed that the intracellular GSH content was dose-dependently increased by treatment of M with cystine, and was increased further by the addition of glutamate (Rimaniol et al
BPC 157, in contrast, induced faster rates of healing and induced full functional restoration, which is also in agreement with the aforementioned studies on tendons (Krivic et al
However, more reliable information is needed to determine whether it might be helpful
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