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It is not an approved dietary supplement ingredient under the Dietary Supplement Health and Education Act (DSHEA) framework because it has not been grandfathered in as a pre-DSHEA ingredient and is not a recognized vitamin, mineral, herb, or botanical
These side effects are the focus of Bart C

While Glutathione itself is a naturally occurring substance, the FDA does not currently approve it specifically for injection use in skin whitening

This is because these ingredients work synergisticallyvitamin C helps regenerate glutathione, whilst other brightening agents target different pathways in melanin production