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8 Together with our findings that the effects of GLP-1 receptor agonists are consistent regardless of SGLT2 inhibitor use, the totality of the worldwide placebo-controlled randomized evidence indicates that combination GLP-1 receptor agonists and SGLT2 inhibitors are likely to have independent and additive effects on clinical outcomes in people with type 2 diabetes

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9 Gs and Gq signaling in DVC Glp1r neurons differentially drive activation of AP/NTS and downstream elPBN

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