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If you look closely at the bottom panels of the 2 graphs above for loss of body weight, the participants in the new trial had 40% less weight loss than in the previous trial of obese, non-diabetic participants
Five repeats were analyzed in each condition
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Semaglutide and tirzepatide are FDA-approved with extensive clinical trial data showing average 15-20% body weight loss, improvements in cardiovascular health markers, reduction in obesity-related disease risk, and excellent safety profile with proper medical supervision
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