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The markers of carbohydrate metabolism were glucose (CV 5%), insulin (CV 7%), and insulin resistance (IR), which was calculated as the homeostatic model assessment index [HOMA-IR=insulin (mU/l) x glucose (mmol/l)/22.5]

Important cautions: History of medullary thyroid carcinoma (MTC) or MEN2 , pancreatitis , gallbladder disease, severe GI disorders, certain drug interactions, and pregnancy/breastfeeding considerations

B12 is safe on its own, but a few conditions call for extra care, which is why a provider reviews your history before treatment: Leber's hereditary optic neuropathy, a rare inherited eye condition, where certain forms of B12 may be a concern for the optic nerve