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The IC 50 values for lowering cholesterol accumulation for three of the four compounds ( 3 , 6 , 10 ) were in the mid-nanomolar to low-micromolar range
Reactivity of the human thioltransferase (glutaredoxin) C7S, C25S, C78S, C82S mutant and NMR solution structure of its glutathionyl mixed disulfide intermediate reflect catalytic specificity
Brain glucagon-like peptide 1 signaling controls the onset of high-fat diet-induced insulin resistance and reduces energy expenditure
Similar to the RoA, additional investigation based on subgroup analysis of dosage and duration of treatment revealed no significant SMD in subgroups (Supplementary Figure 2)
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