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The landscape is evolving rapidly
For most people, 90 degrees (straight in) works at abdominal sites where there is ample fat, while 45 degrees works better at thigh sites or for leaner individuals
That evidence may matter significantly for patients with: Prior heart attack Stroke history Significant cardiovascular risk factors Patients Who Prefer Weekly Rather Than Daily Dosing Some people are actually more consistent with once-weekly routines than with daily medications
If anxiety occurs, it is more likely during the initial weeks as the body adjusts to the medication
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