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Much of the focus on the impact of GLP-1 receptor agonists (and combination drugs with components that target other receptors such as gastric inhibitory polypeptide collectively termed GLP-1s in this article) to date has been on their potential to improve long-term health outcomes for people with type 2 diabetes, obesity, and related cardiovascular diseases

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Other monitored potential side effects include Nausea Vomiting Diarrhea Constipation Decreased appetite Transient increases in heart rate Gallbladder-related events (e.g., cholelithiasis) Elevated pancreatic enzymes These side effects typically diminish over time with continued treatment and appropriate dose titration