At a critical point in the melanogenic pathway (asterisk, Fig
For example, the study also showed that alopecia was more likely in patients with thyroid disease or other endocrine disorders, which could indicate a connection to baseline hormonal, autoimmune or dermatologic risk factors, said Venky Soundararajan, who led the nference study
In a separate meta-analysis, 21.7% of overweight/obese children were diagnosed with depression and 39.8% with anxiety, but only 18.0% of non-overweight/non-obese children had depression and 14.0% had anxiety, further stressing the importance of prioritizing effective treatment strategies4
[17] In November 2025, Pfizer won a bidding war with Novo Nordisk, acquiring obesity drug developer, Metsera