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Additionally, harmful metabolites such as TMAO, derived from microbial metabolism of certain dietary components, induce mitochondrial dysfunction and ROS generation, accelerating neurodegeneration and AD pathology
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The peptide upregulates MMP-2 expression in dermal fibroblasts by 85%, facilitating breakdown of damaged collagen and enabling cellular migration through dense matrix environments, while simultaneously enhancing production of tissue inhibitors of metalloproteinases (TIMPs) to prevent excessive degradation
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