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This process is crucial because superoxide anions are among the first ROS to be produced during oxidative stress, particularly in mitochondria, which are key sources of ROS in sperm cells

J Clin Endocrinol Metab (1997) 82(12):4196200.10.1210/jcem.82.12.4450 107 HolmesAGMesaJLNeillBAChungJCareyALSteinbergGRet alProlonged interleukin-6 administration enhances glucose tolerance and increases skeletal muscle PPARalpha and UCP2 expression in rats