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Here, we provide the first evidence of improved healthspan and age-related survival with a therapeutic mAb by demonstrating that treatment with an IGF-1R antagonist in older mice significantly and preferentially improves several indices of healthspan, reduced death from neoplastic disease, and increased mean and median lifespan in females
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Mounjaro has been shown to produce an average 15.7% reduction in body weight, with almost a third of participants experiencing a reduction exceeding 20%
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