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[4] Based on animal research, it is thought that the increased methylmalonyl-CoA hydrolyzes to form methylmalonate (methylmalonic acid), a neurotoxic dicarboxylic acid, causing neurological deterioration
The mixture was centrifuged, and the filtrate was collected
Given these serious iatrogenic consequences, hPSC transplantation currently remains viable only for the treatment of critical, life-threatening conditions where the potential benefits outweigh these substantial risks
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