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This enzyme catalyzes the N-methylation of nicotinamide using S-adenosyl-L-methionine (SAM) as a methyl donor, effectively creating a "metabolic drain" that depletes both NAD+ precursors and cellular methylation capacity
If youve been struggling with low energy, mood swings, or frequent colds, your body might be trying to tell you it needs a little extra support
(2025) 12:e2411479
[42] The EFSA also reviewed the safety question and reached the same conclusion as in the United Statesthat there was not sufficient evidence to set a UL for vitamin B 12
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