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Fatigue and energy changes Some users report feeling unusually tired during the first weeks of treatment

some children showed sustained increases in growth velocity over 12-36 months of therapy, while others responded less robustly (somatropin GH is generally more potent)

Impaired Insulin Sensitivity and Fat Metabolism Low testosterone is linked to poorer insulin sensitivity, meaning the body struggles to manage blood sugar efficiently

While it is generally safe and effective, there are some important interactions to be aware of: Oral Hypoglycemic Agents: Semaglutide can interact with other diabetes medications that lower blood sugar, such as insulin or sulfonylureas