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Practically, this means setting different goals, allowing more time to increase the dose, and using monitoring methods that focus on early symptom signs and how well people stick to the treatment, rather than only looking at blood sugar numbers
Multiple systems may decompensate simultaneously
Furthermore, vagotomy abolishes the effect of GLP-1 on food intake, while more selective subdiaphragmatic vagal deafferentation attenuates the inhibitory effect of higher doses of intraperitoneal GLP-1 (100 nmol/kg) 136
Being overweight or obese places you at risk for a wide range of health conditions including heart disease, diabetes, stroke, sleep apnea, and mental health conditions like depression and anxiety [2]
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