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Human Metabolism of Lapatinib, a Dual Kinase Inhibitor: Implications for Hepatotoxicity
Adult-onset functional cysteine deficiency from chronic dietary inadequacy, malabsorption (post-bariatric surgery, celiac disease, inflammatory bowel disease), or methylation cycle blocks (severe B12, folate, or B6 deficiency) represents an acquired form
The detection limit was 15.9 nmol/l (2.8 g/l) and the assay was linear between 45 and 8041 nmol/l (8 and 1417 g/l)
In 2012, Dixon et al
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