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Akkermansia muciniphila , Bacteroides thetaiotaomicron , Bacteroides vulgatus , Faecalibacterium prausnitzii , Ruminococcus bromii , and Roseburia ) have been gradually identified and considered to have the potential for treating metabolic diseases due to the development of culturing methodologies and genome and metagenome sequencing techniques [93, 212,213,214,215,216,217]