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Semaglutide for weight loss is not meant for treatment of severe obesity and semaglutide isnt a great option for treatment of obesity when compared to bariatric surgery (Semaglutide is an option for those whose BMIs are less than 40)

Our previous studies, using in vitro cell culture as well as in vivo animal models have also demonstrated that enzymes cytochrome c oxidase (Complex IV) and aconitase are extremely sensitive to mitochondrial-ROS induced oxidative stress in comparison to other complexes [23],[38],[42],[43]

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Lab and/or medical tests (such as kidney function, fasting blood glucose, hemoglobin A1c) should be done while you are taking this medication