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If symptoms do occur, dose reduction often helps
Excessive FAs in the circulatory system promote insulin secretion from pancreatic beta cells, upregulate the expression of renal uric acid reabsorption proteins Glucose transporter type 9 (GLUT9) and urate transporter 1 (URAT1), and reduce the level of uric acid excretion protein ATP-binding cassette transporter G2 (ABCG2), resulting in elevated serum uric acid levels ( Figure 4 )
When to Contact Your PlexusDx Provider Mild nausea, reduced appetite, and slight fatigue are expected and usually resolve within days
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