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Founded in 2012 by a team of scientists from Harvard, Stanford, UC Berkeley, and Johns Hopkins, and led by Co-founder and CEO Colleen Cutcliffe, Ph.D., Pendulum translates cutting-edge microbiome research into clinically studied, targeted microbial solutions

The microsomes were incubated with 500 M solutions of Dihexa, piroxicam, verapamil, and 7-ethoxycoumarin, as controls for low, moderate, and highly metabolized compounds, respectively, in 0.1 M Tris buffer with an NADPH-regenerating system at 37C

To mitigate potential artifacts arising from low-quality alignments, we also employed Gblocks (v0.91b) Citation33 to select conserved blocks from the multiple sequence alignment prior to phylogenetic tree construction

Inflammation in gout: mechanisms and therapeutic targets