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Hence, one melatonin molecule and its associated metabolites could scavenge a large number of reactive species, and thus, the overall antioxidant capacity of melatonin is believed to be greater than that of other well-known antioxidants, such as vitamin C and vitamin E, under in vitro or in vivo conditions 1 2 3 al

These results suggest that during early hepatocarcinogenesis, aberrantly expressed MOZ may induce GSTP1 expression through the NF-E2-related factor 2 (Nrf2)-mediated pathway

Constipation may also prolong contact with biliary metabolites and allow more deconjugation and reabsorption

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