Thus, it is recommended to investigate for this AE in SGLT2i-treated patients with symptoms of ketoacidosis, such as nausea, vomiting, abdominal pain, ketonuria, and/or ketonemia, regardless of the current glucose status [74]
Possible side effects may include nausea, vomiting, diarrhea, constipation, abdominal discomfort, appetite changes, or other symptoms
That extra pathway is one reason researchers are interested in retatrutide, but it is also a reason not to assume its risk profile is identical to tirzepatides
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