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While experimental animal studies suggest that treatments involving NAD may decrease oxidative stress, neuroinflammation, and positively impact the expression of growth factors and mitochondrial function, various studies are still underway to investigate the potential impact on memory, focus and mental clarity in humans

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Moreover, we observed a direct effect of metformin on glutamate transporters, where the compound prevented glycation, by facilitating enzymatic phosphorylation close to Lys residues, suggesting a new neuroprotective role of metformin via PKC in preventing dysfunction in glutamatergic system induced by MG