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Preclinical evidence in rats and mice points to the caudal brainstem and the mediobasal hypothalamus as sites that are necessary and sufficient for the ability of systemically administered GLP-1R agonists to reduce food intake, Rinaman said
Over time, that can make alcohol feel less rewarding, thereby subduing the craving cycle that keeps you coming back for more
This dual mechanism produces research outcomes that single-receptor compounds cannot replicate under equivalent experimental conditions
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