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Its important to see a doctor quickly if any of the following are true: There are signs of possible infection (such as redness, warmth, or a fever) Your leg is swollen and pale or unusually cool You have calf pain after a period of prolonged sitting You have swelling in both legs along with breathing problems Any serious pain develops suddenly While leg pain usually isnt a medical emergency, you should seek immediate medical attention if any of the following applies to your pain: Youre unable to walk or stand You develop pain, swelling, redness, or warmth in your calf You have a sudden injury with a deep cut or exposed tissue You heard a pop or grinding sound when you injured your leg Medication Options Common over-the-counter medications to help relieve leg pain include acetaminophen and nonsteroidal anti-inflammatory medications (NSAIDs), such as aspirin or ibuprofen

OKeefe SJD, Li JV, Lahti L, Ou J, Carbonero F, Mohammed K, et al

This makes provider review, product sourcing, dosing, and monitoring especially important

Science (80-.)