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Reeves GK, Pirie K, Beral V, Green J, Spencer E, Bull D, et al
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They were even named 2023s breakthrough of the year by Science magazine
Ex-4 inhibits oxidized LDL-induced macrophage foam cell formation by downregulating several inflammatory and adhesion molecules in monocytes and macrophages to suppress their accumulation in the arterial wall ( in vivo laser injury model of arterial thrombosis ( Evidence from animal studies suggests that GLP-1-based therapies may be used as cardio- or neuroprotectants, suggests that GLP-1RAs and Dipeptidyl Peptidase-4 inhibitors (DPP-4is) may provide neuroprotection (37)
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