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According to the Wegovy SmPC and NHS commissioning policies, treatment should be discontinued if a patient has not lost at least 5% of their initial body weight after 12 weeks on the maintenance dose of 2.4 mg

These salt forms of GLP-1s have not been proven safe and effective in humans or approved by the FDA, Basina noted, adding that effectiveness can be different due to the salt form differences. Additives To differentiate their products from the FDA-approved GLP-1s, many compounders add extra ingredients most commonly vitamin B12, but also B6, niacinamide, glycine or carnitine that have no proven benefit for weight loss or diabetes management

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