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The JNK pathway in Drosophila is regulated by Basket (Bsk), which, upon activation, can activate the transcription of target genes whose activity aims to reduce cellular stress

The peptide stimulates both synthesis and breakdown of ECM components while modulating the activity of both metalloproteinases and their inhibitors, creating dynamic matrix remodeling that allows tissue reconstruction without excessive scar formation

Falutz, Julian, et al

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