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The semaglutide dosage chart below can help guide you through your weight loss management journey: Weeks 1-4: 0.25 mg, weekly injection dosage Weeks 4-8: 0.5 mg, weekly injection dosage Weeks 8-12: 1 mg, weekly injection dosage Weeks 13+: Up to 2.4 mg, weekly injection dosage While this is the average plan for many people, your individual path may be different