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Avoid Over-the-Counter Medications Some over-the-counter medications, like nonsteroidal anti-inflammatory drugs (NSAIDs), can harm your kidneys if taken frequently

Like any medication, they can come with side effects like nausea, bloating, or fatigue (especially at higher doses)

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Another trial, SOUL (NCT03914326), has now been initiated to overcome the shortcomings of PIONEER 6 with a primary endpoint focused at proving CV superiority vs placebo