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The AAFPs evidence-based clinical review states directly: Oral administration of high-dose vitamin B12 (1 to 2 mg daily) is as effective as intramuscular administration for correcting anemia and neurologic symptoms in patients with B12 deficiency (Langan RC, Goodbred AJ, American Family Physician, 2017)

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Today, liver transplantation remains the only curative option for Wilson disease, but it is associated with immunosuppression for life and significant morbidity.

For a deeper dive into the clinical background, the National Center for Biotechnology Information (NCBI) provides extensive literature on its mechanisms