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renal impairment can further exacerbate neuropathic symptoms through the accumulation of uremic toxins that adversely affect nerve function
FrontiersIn.org Cardiovascular Diabetology
The FDA has approved the use of L-carnitine (by mouth or intravenously) treating L-carnitine deficiency caused by certain genetic diseases, end-stage kidney disease, and other disorders
Discussion Compared to individual parameters, composite biomarkers may provide a more robust method for evaluating disease progression in response to a study intervention than a single efficacy outcome [28]
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