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Mutants affected in the transport and degradation of glutathione and glutathione S-conjugates did not exhibit differences in their susceptibility to AITC While glutathione is synthesized in the chloroplast and the cytosol it is also present in the mitochondrion, nucleus and the apoplast, indicating the necessity of transport 56

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This process facilitates signal transduction to inform the plant about infection and enables the initiation of a well-directed defense response (in resistance) or partially directed (in tolerance)