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Acetaminophen and non-steroidal anti-inflammatory drugs (NSAIDs) (eg, aspirin, ibuprofen) are widely used as analgesics and antipyretics (fever-reducers)
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In the prefrontal cortex, increased TDO and KMO expression alongside reduced IDO and KAT shifts metabolism toward QA production, while cerebellar KYNA levels inversely correlate with symptom severity, linking KP dysfunction to 5-HT metabolism and clinical features [235]
Determination of malonic dialdehyde (intermediate product of lipid peroxidation) was carried out by colorimetric method at an interval of wave length = 535-580 nm in serum and hemolysates of erythrocytes after sedimentation of proteins by means of phosphoric-tungstic acid according to Gavrilovs method
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