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Semaglutide shelf life under these conditions has been well documented for branded versions, and compounded versions follow similar patterns when the formulation includes adequate stabilizers
It also warned companies against making certain claims in promotional materials, including stating that compounded products are the same as FDA-approved drugs, use the same active ingredient, or are clinically proven to produce results
In a clinical pharmacology study in subjects with varying degrees of hepatic impairment, no change in tirzepatide PK was observed [see Clinical Pharmacology (12.3)]
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