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In a dedicated MASLD trial, retatrutide resolved liver steatosis in more than 90% of participants at 48 weeks
Common Causes Most Common * Gallstones * Alcohol abuse Other Causes * Hypertriglyceridemia * Hypercalcemia * Trauma * Post-ERCP * Drugs (e.g., azathioprine, thiazides) * Infections (e.g., mumps) * Pancreatic tumors * Idiopathic Clinical Features Symptoms * Sudden severe epigastric pain * Pain radiating to the back * Nausea and vomiting * Abdominal distension * Fever Signs * Epigastric tenderness * Guarding * Tachycardia * Hypotension * Reduced bowel sounds (ileus) * Jaundice (if biliary obstruction) Severe Disease Signs * Grey Turners sign (flank ecchymosis) * Cullens sign (periumbilical ecchymosis) * Shock * Respiratory distress Diagnosis Diagnosis requires at least 2 of the following: 1
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