5-amino-1mq vs mots-c NAD+ / / Blend – 120mg (100mg / 10mg / 10mg) – FMI health MOTS-C Plus 5-Amino-1MQ a Permanent

Animals treated with 5-amino-1MQ showed no signs of toxicity, behavioral changes, or adverse effects at therapeutically effective doses

Selective NNMT inhibitor substrate site-targeting mechanism with IC50 of 1.2 M in reference assay conditions Selectivity over related methyltransferases does not significantly affect other enzymes in the NAD salvage pathway at research concentrations Reduces intracellular 1-methylnicotinamide (1-MNA) formation in cell-based assay models Studied in adipocyte, liver, and skeletal muscle cell-based research models examining NNMT-dependent methylation pathway dynamics Referenced at Sigma-Aldrich (SML2832) and in peer-reviewed literature on NNMT enzyme biology Membrane-permeable quaternary quinolinium scaffold studied for intracellular NNMT target engagement in cell-based models Batch and lot identifiers on all labeling for full laboratory documentation compliance Research Background 5-Amino-1MQ was first characterized as a selective NNMT inhibitor in published research literature in 2018

Allow the vial to reach room temperature before opening so condensation does not settle on the contents

VEGF seems to be a signaling protein, reportedly involved in angiogenesis, a process that may be responsible for the formation of new blood vessels from existing vasculature