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FDA-approved peptides like semaglutide, tirzepatide, and tesamorelin have undergone extensive clinical trials involving thousands of participants and have established safety profiles
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(1993): Dizocilpine antagonizes the effect of chronic imipramine on learned helplessness in rats
The compound has progressed through Phase I and Phase II trials with promising results, demonstrating both efficacy and safety in multiple patient populations
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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