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Long-term safety data for this combination is limited
Cagrilintide is a synthetic peptide that mimics the effects of amylin, a hormone that regulates appetite and blood sugar
This combination is not typically paired with pramlintide, since cagrilintide already covers amylin signaling and pramlintide is a short-acting amylin analog without new pathway coverage
The trial escalation tables stepped the amount up on a monthly cadence, beginning in the low single-digit milligram range and only advancing once the prior level felt comfortable
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