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Senescent cells, despite their pro-inflammatory SASP, also suppress tumor progression in some contexts through 'senescence surveillance'nearby immune cells recognize and destroy newly senescent cells, including pre-malignant cells undergoing oncogene-induced senescence

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Treatment with 5-amino-1mq upregulates proliferationrelated genes (Ki67, PCNA), promotes cell cycle progression, and improves cell fusion efficiency to form more multinucleated myotubes, achieving functional levels similar to those of young mice.Additionally, 5-amino-1mq inhibits muscle stem cell apoptosis, reduces oxidative stress damage, and maintains stemness