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Conjugated linoleic acid has a wide range of health-promoting effects

& Shibayama, K

The almost immediate degradation of GLP-1 in the body raised the question of the mechanisms involved, and inspired by early studies by the German enzymologist, Mentlein ( Because the cleavage activity of DPP-4 is depending on the presence of a penultimate Pro or Ala at the N-terminus, analogs of GLP-1 with substitutions at this position should be protected, and analogs with Ser, Val, or alpha-aminobutyric acid remained biologically active (116)

The prescription of such aids should be tailored by a physiotherapist or orthotist based on a comprehensive biomechanical assessment (Zhang et al., 2020)