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Cells adapt to serine deprivation via the de novo serine synthesis pathway (SSP), which diverts glycolytic intermediates (e.g., 3-phosphoglycerate) into serine biosynthesis under PKM2 inhibition [19, 20]

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For example, TP53 deletion in colorectal cancer cells increases ferroptosis sensitivity by activating DPP4-mediated NOX1 pathway [70]

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12 Nhc im Trong khi s dng c th gy ra tnh trng ni mn, tuy nhin hin tng ny s ht sau khi ngng thuc

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